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Characterization and distribution of Langerhans cells in rat corneal epithelium |
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Characterization and distribution of Langerhans cells in rat corneal epithelium |
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作者:陈文生 文章来源:天津医科大学眼科中心 点击数:3169 更新时间:2008/1/5
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Purpose. To investigate the characterization and distribution of LCs in normal rat corneal epithelium.
Methods. Normal and inflamed rat corneal tissues were stained for CD11c, MHC class II, B7 and CD3.
Results. The expression of the activation markers CD80 and CD86 by MHC class II+ LCs was present in the limbal basal epithelium after corneal inflammation.
Conclusions. MHC class II+ LCs in the limbal basal epithelium can be stimulated to proliferate in response to the inflammatory reaction of the central corneal epithelium.
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